Today there are a lot of medications to treat headaches and Migraines. As you can see from the list below there are many medications used to successfully treat both headache and migraine, and for their prevention. Many people find that rather than a single medication, it turns out that a combination is sometimes more successful.
The following list of medications are successfully used by some headache and Migraine patients as preventive medications. They're listed first by class, then generic names followed by brand names.
Methylergonovine (Methergine (the only ergot used as a preventive))
Leukotriene Blockers
Montelukast (Singulair)
Zafirlukast (Accolate)
Zyleuton (Zyflo)
Others
Baclofen (Lioresal)
Botulinum Toxin Type A (Botox)
Memantine (Namenda)
Dietary Supplements
Coenzyme Q10
Feverfew
Butterbur (Petadolex)
Magnesium
Vitamin B2
5-HTP (Check carefully with doctor because of interactions with meds including triptans and SSRIs)
Lecithin
Melatonin
References:
Thanks goes to the American Academy of Neurology Practice Guidelines, September, 2000, Nahib M., MD; Silberstein, Stephen D., Md, FACP; Frietag, Frederick G., DO; Gilbert, Thomas T., MD, Frishberg, Benjamin M., MD. "Evidence-Based Guidelines for Migraine Headache in the Primary Care Setting: Pharmacological Management for Prevention of Migraine."
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