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Medications for Migraines
Today there are a lot of medications to treat headaches and Migraines. As you can see from the list below there are many medications used to successfully treat both headache and migraine, and for their prevention. Many people find that rather than a single medication, it turns out that a combination is sometimes more successful.
The following list of medications are successfully used by some headache and Migraine patients as preventive medications. They're listed first by class, then generic names followed by brand names.
Antihypertensives (blood pressure meds)
- Clonidine (Catapres)
- Guanfacine (Tenex)
ACE Inhibitors:
- Benazepril (Lotensin)
- Captopril (Capoten)
- Enalapril (Vasotec)
- Fosinopril (Monopril)
- Lisinopril (Zestril, Prinivil)
- Moexipril (Univasc)
- Perindopril (Aceon)
- Quinapril (Accupril)
- Ramipril (Altace)
- Trandolapril (Mavik)
Alzheimer's/Dementia Medicaton
Angiotensin II Inhibitors
- Candesartan (Atacand)
- Eprosartan (Teveten)
- Irbesartan (Avapro)
- Losartan (Cozaar)
- Olmesartan (Benicar)
- Telmisartan (Midcardis)
- Valsartan (Diovan)
Beta Blockers
- Acebutolol (Secral)
- Atenolol (Tenormin)
- Betaxolol (Kerlone)
- Bisoprolol (Zebeta, Emconcor)
- Cartelol (Cartrol)
- Labetalol (Normodyne, Trandate)
- Metoprolol (Lopressor)
- Nadolol (Corgard)
- Penbutololm aka Levatol)
- Pindolol (Visken, Syn-Pindolol)
- Propranolol (Inderal)
- Timolol (Blocadren)
Calcium Channel Blockers
- Amlodipine (Norvasc)
- Bepridil (Vascor)
- Diltiazem (Cardizem, Tiazac)
- Felodipine (Plendil)
- Flunarizine (Sibelium (Canada))
- Isradipine (DynaCirc)
- Nicardipine (Cardene)
- Nifedipine (Adalat, Procardia)
- Nimodipine (Nimotop)
- Nisoldipine (Sular)
- Verapamil (Calan, Verelan, Isoptin
Antihistamines
- Cyproheptadine (Periactin)
- Pizotifen (Sandomigran (UK))
Tricyclic Antidepressants (TCAs)
- Amitriptyline (Endep)
- Amoxapine (Asendin)
- Clomipramine, aka, Anafranil)
- Desipramine (Norpramin)
- Doxepin (Sinequan)
- Imipramine (Norfranil, Tofranil)
- Nortriptyline (Pamelor, Aventyl)
- Protriptyline (Vivactil)
- Trimipramine (Surmontil)
MAOI Antidepressants
- Isocarboxazid (Marplan)
- Phenelzine (Nardil)
- Tranylcypromine (Parnate)
Other Antidepressants
Selective serotonin reuptake inhibitors (SSRIs)
- Citalopram (Celexa)
- Escitalopram oxalate (Lexapro)
- Fluoxetine (Prozac)
- Fluvoxamine (Luvox)
- Paroxetine (Paxil)
- Sertraline (Zoloft)
Selective serotonin and norepinephrine reuptake inhibitors (SSNRIs)
- Duloxetine hydrochloride (Cymbalta)
- Venlafaxine (Effexor, Effexor XR)
ADHD Medications
- Dextroamphetamine (Adderall)
- Atomoxetine HCl (Strattera)
- Methylphenidate HCl (Concerta, Ritalin)
- Pemoline (Cylert)
Arthritis Meds, Cox-2 Enzyme Inhibitors
Muscle Relaxants
- Carisoprodol (Soma)
- Cyclobenzaprine (Flexeril)
- Lioresal (Baclofen)
- Metaxalone (Skelaxin)
- Tizanidine (Zanaflex)
Antiseizure medications
- Carbamazepine (Tegretol)
- Clonazepam, Klonopin)
- Clorazepate (Tranxene)
- Divalproex (Depakote)
-
Gabapentin (Neurontin)
- Levetiracetam, Keppra)
- Lamotrigine (Lamictal)
-
Oxcarbazepine, Trileptal)
- Tiagabine (Gabitril)
- Topiramate (Topamax)
-
Valproate Sodium (Depacon)
- Zonisamide (Zonegran)
- Pregabalin (Lyrica)
Ergot Alkaloid
- Methylergonovine (Methergine (the only ergot used as a preventive))
Leukotriene Blockers
- Montelukast (Singulair)
- Zafirlukast (Accolate)
- Zyleuton (Zyflo)
Others
- Baclofen (Lioresal)
- Botulinum Toxin Type A (Botox)
- Memantine (Namenda)
Dietary Supplements
- Coenzyme Q10
- Feverfew
- Butterbur (Petadolex)
- Magnesium
- Vitamin B2
- 5-HTP (Check carefully with doctor because of interactions with meds including triptans and SSRIs)
- Lecithin
- Melatonin
References:
Thanks goes to the American Academy of Neurology Practice Guidelines, September, 2000, Nahib M., MD; Silberstein, Stephen D., Md, FACP; Frietag, Frederick G., DO; Gilbert, Thomas T., MD, Frishberg, Benjamin M., MD. "Evidence-Based Guidelines for Migraine Headache in the Primary Care Setting: Pharmacological Management for Prevention of Migraine."
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